Skrillex and ISOxo Reunite for Explosive New Single ‘Smoke’

Skrillex has officially teamed up with San Diego-based trap producer ISOxo for their latest collaborative effort, ‘Smoke’. This release marks the second time the two artists have combined their distinct production styles, following the success of last year’s track, ‘Fuze’.

The new single features additional vocal contributions from Cristale and TeeZandos, adding a gritty, rhythmic layer to the duo’s signature high-octane sound. Fans can listen to the track below:

‘Smoke’ arrives during a particularly prolific period for Skrillex. The producer has maintained a relentless pace throughout 2026, including the recent collaboration ‘Duro’ with Young Miko and an extensive tour across South America. His live presence remains as impactful as ever, highlighted by a surprise b2b set with BZRP at Ultra Miami this past March.

This latest single follows the momentum generated by his ‘Kora’ EP, which was released earlier this year. As Skrillex continues to bridge the gap between experimental sound design and club-ready anthems, ‘Smoke’ serves as another testament to his ongoing influence in the electronic music landscape.